Lizzie Borden High's class of '72 are going through the motions at their tenth-year reunion, until deranged alum Walter Baylor, driven insane by a sadistic senior-year prank, escapes from the mental institution and crashes the party. When guests start getting bumped off, the other alumni, including snooty yacht salesman Bob Spinnaker, class tease Bunny Packard, and class zero Gary Nash, spring into action to uncover the culprit.
An 'Airplane!'-style spoof of hospital soap operas—a brilliant young trainee can't stand the sight of blood; a doctor romances the head nurse in order to get the key to the drugs cabinet; and there's a mafioso on the loose disguised as a woman.
Nurse Linda Lovelace works for libidinous sex therapist Dr. Jayson. One of the patients she is treating is Dilbert Lamb, a meek geek who's harboring plans for a top secret government computer. Both the KGB and FBI alike attempt to enlist Lovelace in order to obtain the data on the computer.