Claire
Matt Franklin (Topher Grace) é um jovem de 22 anos recém-graduado que não sabe o que fazer da vida. Ele poderia ter um belo emprego em um escritório ganhando muito dinheiro, mas prefere trabalhar como balconista em uma vídeo locadora. Quando Tori Frederking (Teresa Palmer), a garota por quem era apaixonado no colégio entra no estabelecimento, ele decide tentar conquistá-la. Junto com Wendy (Anna Faris), sua irmã, e seu melhor amigo Barry (Dan Fogler), Matt aproveitará o convite para a festa de Kyle Masterson (Chris Pratt) para ter a melhor noite de todas.
Charlotte
A middle-American teenage boy who is affected by 9/11, terrorism, and the war in Iraq becomes involved in an isolated high school altercation that escalates into a hate crime that shocks the entire nation.
Young Girl
Raven (Darlena Tejeiro) and Ashley (Andrea Bogart), two young women returning from a rock-climbing expedition, find themselves harassed by a group of bikers at a dusty bar in the desert. With surprise and guile on their side, the girls escape by stealing the leader's bike. Within minutes the furious biker gang is in hot pursuit through the hazardous terrain. Believing they have evaded the bikers, the girls discover a satchel of cash on their damaged bike and stumble across the desert to a small motel. The owner, Ned (Joe Goodrich), has agreed to drive them into town when suddenly the bikers appear, and they're looking for payback and the money.
Lisa
The vampires have taken over suburbia, and the only hope for escape is to dismantle the white picket fences and drive them through the hearts of the undead in this tale of bloodlust.