Robert McCall finds himself at home in Southern Italy but he discovers his friends are under the control of local crime bosses. As events turn deadly, McCall knows what he has to do: become his friends' protector by taking on the mafia.
O trabalho de Cobra, Nero e Mazinga é colocar ordem no caos, mesmo que seja necessário empregar a força bruta. Com a chegada de Adriano na equipe, eles começam a questionar o uso da violência.
