Mathilde (Audrey Tautou) e Manech (Gaspard Ulliel) cresceram juntos e descobriram o amor. A 1ª Guerra Mundial os separa. Ao fim da guerra Mathilde faz uma incansável busca para encontrar Manech.
The beautiful Parisian courtesan Marguerite Gauthier (Cristiana Réali), who is called a "Lady of The Camellia" because of the preference for these flowers, has many devotees among Parisian aristocrats. He really loves one - young Armand Duval (Michaël Cohen). Under the influence of the beloved father's pleas, and despite himself, he declares to Armand that he no longer loves him. She is suffering from tuberculosis, but if possible, she is in company, and renews contacts with rich devotees. Armand tries to forget about her. One evening, at a party, their paths cross again.
As a result of an automobile accident, a sophisticated TV producer meets her car mechanic/blue collar nemesis. They start a comic affair, but can they reconcile their totally different worlds?