Orangutan (voice)
Após um pequeno acidente, o Doutor John Dolittle recupera o dom de infância de conversar com animais. Mas esta habilidade rara começa a causar muitas confusões na vida do médico, que agora tem que cuidar de macacos embriagados e leões deprimidos que precisam de ajuda. O comportamento estranho de Dr. Dolittle acaba fazendo com que ele vá parar em um hospital psiquiátrico.
Dad Smith
Eleven-year-old North has had it with his parents. They are always busy with their careers and don't give North the attention he needs, so he files a lawsuit against them. The judge rules that North should either find new parents or return to his own parents within two months. Thus North starts off on a journey around the world to find parents that really care about him.
Mr. Zucker
Dumped by his fiancée, Clifford Godfrey goes on vacation anyway where he ends up torn between a sober party girl and his travel agent.
Officer John
Four very different women, best friends during high school many years earlier, gather in the small town where they grew up for a reunion as bridesmaids in preparation for a wedding for a fifth friend.
