Professor Archibald Chagrijn exposes the world to his blubbering gas, which makes people sad and causes them to cry. Bassie proves immune to the blubbering gas -- as he has had an overdose of laughing gas. The professor is hiding on the Canary Islands, but Bassie and Adriaan manage to track him down.
While the residents of Runichem are busy preparing for the approaching centenary, an art theft takes place in a villa. The same evening, an officer is shot at an alcohol check. When Wilbur tries to call home from the community center that night, the phone interferes and he hears a fragment of a conversation related to criminal activities. Wilbur and his friend Aristides decide to investigate this mysterious case, with the help of Akkie, daughter of inspector Swaan, and grandfather Quarles. This film is based on the second season of the Dutch tv series 'Q & Q'.