In the near future, a pandemic has ravaged the earth. Fear, greed and destruction have made way for such terrors as famine, pirates, and zombies. Cairo Yazid's only chance for survival is to join forces with a curmudgeon, Solomon, also still untouched by the fatal virus, and he is the only one who knows the secret location of the safe place known simply as The Cove.
Dois pesquisadores, o grandalhão Dr. Hasse (Arnold Schwarzenegger) e o pequeno e malandro Dr. Arbogast (Danny DeVito), desenvolvem uma droga para auxiliar a gravidez. Impedidos de continuar o projeto, a dupla rouba um óvulo e o implanta na barriga do Dr. Hasse. E assim passam a testar a droga, a partir das reações do grandalhão durante os 9 meses de gestação.
