Bandleader Kay Kyser takes his troupe of nutty musicians, goofball comics and pretty girl singers on a tour around the world to entertain the troops during World War II.
A young soldier on a pass in New York City visits the famed Stage Door Canteen, where famous stars of the theater and films appear and host a recreational center for servicemen during the war. The soldier meets a pretty young hostess and they enjoy the many entertainers and a growing romance
J. D. Forbes, head of the almost-bankrupt Four Star Studios in Hollywood contacts band leader Kay Kyser, who puts on a radio and-live theatre program called "The Kollege of Musical Knowledge," to appear in films. When manager Chuck Deems gets the studio offer, he and band members Ginny Simms, Sully Mason, Ish Kabiddle, Harry Babbitt and the others are all fired up at the prospect of going to Hollywood and working in the movies, but band-leader Kay is all against it and says his old grandmother has told him to stay in his own back yard, but he relents. Once there, Stacey Delmore, a Four Star associate producer left in charge of the studio while Forbes is out of town, discovers that the screenplay writers have prepared a script that has Kay Kyser playing a glamorous lover in an exotic European setting.