Os azarados irmãos Lars e Ernie Smuntz não pensam muito na velha mansão que herdaram... até que descobrem que sua dilapidada propriedade vale milhões. Mas antes de entrar no dinheiro, eles precisam se livrar do único e teimoso morador: um minúsculo e resistente ratinho. E então o que parecia brincadeira de criança torna-se uma batalha de desvairadas proporções.
Shakes plods about his duties as party clown, and uses all of his free time getting seriously drunk. Binky, another clown, wins the spot on a local kiddie show, which depresses Shakes even more, and his boss threatens him with unemployment if he can't get his act under control.
As they enter their third year of medical school, a group of young students must prepare to decide what they intend to specialize in. Somehow, they must impress the Chief of Surgery while learning how to survive the life-and-death area of medicine and the complexity of their everyday lives.
