A plane carrying seven blind people to a convention for the blind in Seattle crashes in the mountains due to severe weather. Only the blind survive the crash and they must make their way back through the wilderness to civilization.
Em Gotham City, Charada, Pinguim, Coringa e Mulher-Gato roubam uma invenção secreta e planejam usá-la de forma maléfica. Além disto, planejam também destruir o Homem-Morcego e o Menino-Prodígio.
Successful and well-liked, Dr. Noah Praetorius becomes the victim of a witchhunt at the hands of Professor Elwell, who disdains Praetorius's unorthodox medical views and also questions his relationship with the mysterious, ever-present Mr. Shunderson.