An American ex-GI takes a job as a truck driver to support his British war bride Connie. It isn't long, however, before Harry is blackmailed into joining a smuggling operation run by a conniving criminal.
Spurred on by the death of his drug-addicted sister at the hands of ruthless narcotics kingpin Frank McNally, U.S. drug enforcement agent Charles Sturgis embarks on an investigation that takes him from New York to London, Lisbon, Rome, Naples and finally Athens in pursuit of McNally's shapely associate, Gina Broger.
Um homem que trabalha para 'The Party' (O Partido) (um império todo poderoso liderado por um homem conhecido apenas como 'Big Brother' (Grande Irmão)) começa a ter pensamentos de rebelião e amor por um colega. Juntos, eles procuram ajudar a derrubar a festa.