The movie tells the story of UMA, played by Alexandra Braun, who lives in Italy and meets a writer, interpreted by the also Venezuelan actor Orlando Delgado. There's is an inexplicable chemistry between both, which would later become a love story that springs up on the wonderful coasts of Gaeta, until crossing the beautiful land of Florence. An accident will change their lives.
O longa é dividido em quatro segmentos. Em um deles, um casal americano (Woody Allen e Judy Davis) viajam para Roma para conhecer a família do noivo de sua filha. Outra história envolve Leopoldo (Roberto Benigni), um homem comum que é confundido com uma estrela de cinema. Um terceiro episódio retrata um arquiteto da Califórnia (Alec Baldwin) que visita a Itália com um grupo de amigos. Por último, temos dois jovens recém-casados que se perdem pelas confusas ruas de Roma.
Reporter Marcello has a brief encounter with Irene while waiting for a train. A young woman who has lost her sight finds herself falling for the voice of a ship's captain she hears over a radio broadcast. Egle, a massage therapist who is soon to be married, finds herself pursuing one last fling with Gabriele -- though the odds are not in her favor, since he happens to be gay. Elena is a young woman with a child who wants to abandon her husband. And Carla wonders if she has any future at all with her lover -- who is married to someone else.