University professor Kenzo Oshima (Hisamatsu Nobumi) is stabbed to death by someone in an alleyway in Tokyo, and Inspector Totsukawa (Takahashi Hideki) and Detective Kamei (Takada Junji) of the Metropolitan Police Department's Investigation Department's Investigative Division 1 arrive on the scene. According to the first finder, the victim died after saying "Totsukawa...". Oshima was famous as the leading authority on mitochondria, but he had never met Totsukawa... Totsukawa is puzzled, but begins to investigate, and discovers that a suspicious man has been caught on a security camera near the crime scene. Seeking a clue, Totsukawa and his colleagues interview associate professor Hayase Yumi (Kurotani Yuka) and the president of a biotechnology company, Koji Nakazono (Nakamura Shunsuke), who was assisting them in their research, to find out what happened. They find out that the man caught on the security camera is none other than their childhood friend, Akaike Shogoro (Matsuo Satoshi).
Mari is a female university student. She takes part in an experiment held by popular VTuber Sophia. When Mari arrives at the place where the experiment is to be held, she notices the place looks like a prison. 12 people participate in the experiment and they are assigned roles of prisoners and prison officers. The experiment takes place over 7 days. Mari is assigned the role of a prison officer. The experiment turns violent.
In this offbeat coming-of-age tale, a charming, rebellious high school dropout named Kanta befriends the kind, provincial Shoji. The two bring out the best in each other, each gaining confidence from their friendship - especially regarding pursuit of the opposite sex. The working class Kanta becomes a sort of unruly anti-hero, maintaining his pride, defiance, and self-assurance even as his prospects seem increasingly grim.