"The Curse" stars Amy Laughlin ("Class of '02") as Frida, a shy, single New York City woman who suffers a mysterious dog bite during a lingerie sale. Soon after, Frida begins to change with the cycle of the moon, becoming more confident, assertive, beautiful...and dangerous. When she wakes up with her sheets soaked in blood, Frida assumes that she has been suffering from a wicked case of PMS. But when the men she dates start dying horrible deaths, Frida must face the possibility she's becoming...a werewolf! There's a reason they call it THE CURSE.
A Corporação Talos desenvolve pesquisas em engenharia genética. Certo dia, o Dr. Foster, um pesquisador da companhia, é atacado por Spot, um sapo contaminado com genes espaciais. Ele começa a sofrer uma mutação aterrorizadora e, talvez, irreversível.