Himeshiro is a wandering yakuza, his father was the best doctor in the eight provinces of the Kanto region, and Himeshiro took over the knowledge of medicine from his father. If he encounters a sick person on the way, he uses his right hand, wrapped in a rosary, to give medical attention, while if he sees a bad person, he draws his sword with his left hand and uses it to punish the evildoers. So he travels on the verge of life and death along the Nakasendo highway...
Isozoemon (Go Kato) was a ronin (masterless samurai) and broke, who lived in a Choya (cheap apartment) in Okazakijoka town with his sick wife, Sugie (Ai Kanzaki). He was also a good swordsman who had taught swordsmanship in Akita a long time ago. He takes such good care of his wife that he is called a wife-loving man. He got involved in a conflict for succession because he pretended to become an officer to please her wife.
