A young playwright who writes porno novels to overcome a writer's block, lives the fantasies of one of his books, while trying to move with his wife from one apartment into a larger one.
Myron Breckinridge flies to Europe to get a sex-change operation and is transformed into the beautiful Myra. She travels to Hollywood, meets up with her rich Uncle Buck and, claiming to be Myron's widow, demands money. Instead, Buck gives Myra a job in his acting school. There, Myra meets aspiring actor Rusty and his girlfriend, Mary Ann. With Myra as catalyst, the trio begin to outrageously expand their sexual horizons.
When 17 year old Joanna comes to Swinging London, she meets a host of colourful characters, discovers the pleasures of casual sex and falls in love. That's when things get complicated.