В результате лабораторных опытов профессора Жеральда Димера над пауками, один из них ускользает, увеличивается в размерах и нападает сначала на скот, а потом на людей...
Rancher Rex Allen receives a summons from his uncle. an old time frontiersman, that he is in trouble. The uncle has been hired to lead a modern-day band of adventurers on a wagon train retracing the route taken by their ancestors 100 years ago. Before Rex can talk to his uncle, the uncle is murdered, and Rex sets out to find the killer and the motive by taking his uncle's place as the leader of the wagon train.
Larry Morgan, a private detective, is hired by a woman who wants Larry to trail her husband. The husband is murdered and, shortly afterwards, the wife is also killed. Larry shuffles through a long list of suspects before revealing the killer...