Chloe and Jack travel to Miami for their honeymoon. Amidst the flashy neon and sunny beaches, they decide that a peyote experience will strengthen their marriage. Unbeknownst to them, they've been given a rare and powerful strand that awakens a desire to eat human flesh. Confronting their toxic relationship, their suite becomes a den of love, lust and resentment as she realizes that the only way to escape this troubled marriage to an emotionally abusive husband is to literally consume him.
A lavish launch party for a new gaming app "Werewolves Awaken" has all the media bigwigs in attendance. The young lead developer, August, is promoted as the star talent driving the game's launch. The festivities are interrupted by a priest who condemns the party guests as "marked for the beast." Convinced it's a publicity stunt, the party-goers disregard the protest until a dead body is found.
After witnessing a brutal crime, things are finally starting to look up for 17 year old high school dropout Chelsea. She's fallen madly in love with Jeff, an older and accomplished man who is promising to give her the life she can only dream of; there's only one hitch...he's still married! To make matters worse, Chelsea finds out she is pregnant and Jeff wants nothing to do with the baby.