Boston pharmacist Tom Craig comes to Sacramento, where he runs afoul of local political boss Britt Dawson, who exacts protection payment from the citizenry. Dawson frames Craig with poisoned medicine, but Craig redeems himself during a Gold Rush epidemic.
A New York radio personality travels to the small town of Fernville to oversee a contest to identify retired safecracker Jimmy Valentine, believed to be living there under an assumed name. The close-knit town of upstanding citizens is understandably upset by this venture, all the moreso when some of its citizens begin to be murdered. The radio personality and the local newspaper's young daughter collaborate on solving the murders while revealing Valentine, who has become one of the suspects.
The Mesquiteers return to Texas after the Civil War to find Army carpetbaggers fighting the local bushwackers. They quickly learn that Capt. Hawks and his men are the culprits and join up with Morgan and his men.
Bob Clemens is a cameraman for newsreels. Assigned to shoot the Swiss ice skater Karen Vadja, he arrives too late, so decides to film a woman skating on a different New York rink and pass her off as Karen. The scheme backfires when promoter Larry Herman takes a look at Bob's film and decides to make the skater a star. Unfortunately, it's actually amateur (and illegal immigrant) Marie Bergin in the newsreel footage, not the great figure skater from Switzerland. Chaos ensues as Bob tries to straighten everybody out.