Victor, a successful and well-respected businessman, is obsessed by the legend that an indigenous woman told him when he was a child. Victor lives a conventional life with a family that knows and complains about his constant infidelities. When the woman is dying, she sends for Victor and her son Jose Francisco, who is working as his chauffeur. They both answer the summons. Their lives take an unexpected turn.
In a bleak near future the world has really gone to seed due to severe pollution. Toxic smog, acid rain, and grotesquely mutated animals are all direct results of this environmental decay. Ruthless industrialist Roberto Cervantes makes matters worse by illegally dumping plutonium. School teacher Irina and professor Axel try to stop Cervantes. Moreover, a giant lethal humanoid rat runs amok in Irina's house.