Gib, a beer-guzzling slob, and Alison, an uptight Ivy-Leaguer, are an unlikely duo stuck together on a cross-country trip during Christmas break. At first they get on each other's nerves but, as time passes, they find their divergent natures complement each other. Now they need to realize what they've already found before it's too late.
Jesse has to get out of Las Vegas quickly and steals a car to drive to L.A. On the way, he shoots a police officer. When he makes it to L.A. he stays with Monica, a girl he has only known for a few days. As the film progresses, the police get closer to him, and the crimes escalate.
When an extortionist threatens to force a multi-suicide unless a huge ransom is paid, only Peter Parker can stop him with his new powers as Spider-Man.