Yuta Okkotsu is a nervous high school student who is suffering from a serious problem—his childhood friend Rika has turned into a curse and won't leave him alone. Since Rika is no ordinary curse, his plight is noticed by Satoru Gojo, a teacher at Jujutsu High, a school where fledgling exorcists learn how to combat curses. Gojo convinces Yuta to enroll, but can he learn enough in time to confront the curse that haunts him?
Leon, who has succeeded the name of Golden Knight "GARO," devotes himself to train a young Makai Knight for the next generation, together with Prince Alfonso of the Valiante Kingdom. Then, they receive an order to exterminate the most beautiful Horror in the world which resides in a neighboring country "Vazelia." At the same time, a young Makai Knight for the next generation is kidnapped by an unknown person. Leon desperately follows them, only to find that he is surrounded by his enemies at a dead end. Then, a Makai Knight Dario who was supposed to be missing for some time suddenly appears and rescues him. Under his guidance, Leon is led to the town where he meets up a totally unexpected person.
On a walk home, Keroro and Fuyuki stumble upon a hidden shrine. Upon exploring it, they end up causing damage to a shining orb within it. That night, Keroro finds a large X on his face, which causes him considerable distraught. The next morning, a breaking news story shows that the X has spread to more than just Keroro, giving the people of Tokyo telepathic abilities, including the Hinata Household and the Keroro Platoon. The Pekoponians seem to think this is a great gift, but the mark may actually be part of a Pekopon invasion older than time itself.
