Following a childhood tragedy, Dewey Cox follows a long and winding road to music stardom. Dewey perseveres through changing musical styles, an addiction to nearly every drug known and bouts of uncontrollable rage.
Three young people on a road trip from Colorado to New Jersey talk to a trucker on their CB radio, then must escape when he turns out to be a psychotic killer.
On its way back to Earth, the space shuttle Nautilus passes through a cloud of alien spores causing its sole occupant, astronaut Steve Thomas to transform into a blood-thirsty monster. The shuttle crashes into a swampy region of central Florida, creating a situation which threatens contagion and/or death to all who encounter the shuttle or its mutated pilot.
