Noel works at an indoor baseball facility with her father where her day-to-day existence is overshadowed by the curse of her family’s lineage: every family member must hit 100 baseballs everyday or the love of their life will die.
Alex, un estudiante de primer año universitario solitario, se ha alejado de sus compañeros, quienes parecen haber resuelto todo este "asunto de la universidad". Pero todo cambia una noche cuando Alex da un salto y asiste a una fiesta en Shithouse, una legendaria fraternidad de fiestas, donde forja una fuerte conexión con Maggie.
Terrified that his mother may not find the important mental stimulation he believes will stave off Alzheimer's Disease, Sam sets out to find her the Perfect Best Friend within her new retirement community, with hilarious and poignant results.