Para la joven Carolina Matilde (Alicia Vikander), casada siendo una adolescente con el rey de Dinamarca Christian VII, es un horror vivir con un marido ciclotímico y estrafalario que propone medidas como nombrar a su perro miembro honorario del Consejo de Estado, o que circulen en Copenhague por la noche carruajes vacíos para recoger a los borrachos. Así las cosas, Carolina se rinde a los encantos del médico personal del rey, un intelectual progresista (Mads Mikkelsen) que se verá dividido entre su lealtad al rey, su amor a la reina y su oportunidad de convertir una Dinamarca aún medieval en un país ilustrado.
Lovers & Murderers is about the ongoing war between those who have and those who want to have what the others have. The have-nots see themselves as poor victims trying to get for themselves what is justly theirs. But when the have-nots become haves, they continue to see themselves as victims of the hordes baying for what is justly theirs, and they have neither the energy nor the security to enjoy what they have obtained. The movie takes place in the microcosm of a small apartment building. The principal goal of the young people who share rooms in the building is to move into their own room and, some day, a real apartment. They scheme to get what they're after: form short-lived alliances, petition, frighten, marry, become pregnant, anything that might work. Lovers & Murderers presents Páral's vision of mankind caught in a cyclical process in which ideology pales before the pettiness, cruelty, and self-justification of human nature.