A simple man, Dr. Walter Newman has high aspirations to cure all disease through genetic manipulation. His obsession with his mission draws him deeper into his own dark world, distracting him from his wife Olivia and from his responsibilities to his patients at the Edgewood Asylum. The doctor's loyal but diabolical nurse, Ms. Tinsley, decides to take matters into her own hands and in secret she conducts her own experiment. When Dr. Newman realizes what has been done, a deformed creature that defies nature is created. Part human, part nightmare. Dr. Newman knows what he must do, but is it already too late?
Josh (Breckin Meyer) tiene un gran problema. El estudia en Ithaca (Nueva York), Tiffany (Rachel Blanchard) su novia desde la infancia, estudia en Austin (Texas). Por error, una cinta de video de Josh manteniendo relaciones sexuales con Beth (Amy Smart) ha sido enviada a Tiffany. Ahora, el tiene solo tres dias para llegar a Texas antes que la cinta. La gran distancia entre Ithaca y Austin convertira esta estridente aventura universitaria en un authentico VIAJE DE PIRADOS.
