In a hellish future where human beings have become stupefied by the state of permanent happiness they have been genetically altered to experience, Jack offers relief via drugs that cause his customers the welcome phenomenon of pain. But when Jack receives a mysterious videotape of his dead father, he sets out to unmask the dangerous conspiracy that has created this dystopian world.
40-year-old Arnold Gardner is put in charge of the talk show "The Twenty-fifth Hour" after the death of the former host Duncan Mackay. His role on screen creates immediate interest and the program becomes a great success with TV audiences. This proves to be a period of great satisfaction for Arnold, but his childhood friend, Eddie Greenberg, suddenly comes on the scene. Eddie is ill and frustrated by lack of success, and is so resentful and envious of Arnold's fame that he wants him to make a full public confession of a "sin" he committed in his young days.
When an explosion at a top-secret government lab injures an elderly janitor, no one could have expected the terrifying results. Exposure to mysterious chemicals causes him to undergo a bizarre transformation. He is slowly... incredibly... growing younger every day. Now, a ruthless CIA assassin will stop at nothing to take him prisoner and turn him into a government guinea pig. With his future on the line, the janitor goes on the run with his wife and a feisty female agent. All the while, he continues to transform... into a being with powers that are as deadly as they are unimaginable.