The Sisters is an adaptation of the first short story in James Joyce's collected works, Dubliners. Set in 1915 Ireland, it tells the story of a young boy, who reflects upon his time with friend and mentor, Father Flynn, while coming to terms with the Priest's death. As he listens to the conversations of the adults around him and thinks back on his own time with the Father, the boy begins to come to a new understanding about his friend and possibly about himself, as he is confronted with questions of faith, loss and new beginnings.
Ed Altman is a psychiatrist who relocates to Palm Springs, Calif., in order to avoid a lawsuit. However, he happens to wander directly into more trouble when he begins an affair with the rich and beautiful Ally Mercer (Annabel Schofield), who has her own reasons for becoming involved with Ed. Soon Ally's other lover, the volatile Nick, is caught in the intrigue, which results in murder, betrayal and numerous shady dealings.