When a group of students manage to complete Thomas Edison's unfinished "spirit phone" that allows communication with the dead, they are brought to the spirit world by an ancient Incan priest. There they meet historic figures such as Albert Einstein, Buddha, and Friedrich Nietzsche and learn the hidden truths of the cosmos, heaven, hell, and God.
The year is 21XX. Reploids are commonplace now, after Dr. Cain rediscovered Dr. Light's old lab and based several designs off of Dr. Light's original, called "Mega Man X". X, meanwhile, has joined the Maverick Hunters, and works with unit leader Zero under the command of Commander Sigma. It is their job to terminate reploids who have become violent.