Entirely made in California, the film brings together 30 American and European actors in an epic which crosses the mythical territories of that cinematic land from Zabriskie Point to Mulholland Drive. California is revisited through the movie memories incarnated by the very presence of famous actors and actresses. "The American Tetralogy" is a way of staging reality which questions the fictional nature of the movies.
Joe Dirt is a janitor with a mullet hairdo, acid-washed jeans and a dream to find the parents that he lost at the Grand Canyon when he was a belligerent, trailer park-raised eight-year-old. Now, blasting Van Halen in his jacked-up economy car, the irrepressibly optimistic Joe hits the road alone in search of his folks.
A struggling freelance writer, while investigating the transvestite night life, stumbles across a serial killer in action. The two then strike up a bizarre partnership to document the killer's motives and handiwork as a possessed detective struggling with his own personal demons tries to solve the crimes.
A paroled short order cook and a waitress go on the run with a bag of diamonds that accidentally falls into their possession, prompting two warring gangs to come after them.
A depressed housewife whose husband is having an affair contemplates suicide, but changes her mind when she faces death by a killer hired to do her in.