Unrepentant Tennessee moonshine runner Luke Doolin (Robert Mitchum) makes dangerous high-speed deliveries for his liquor-producing father, Vernon (Trevor Bardette), but won't let his younger brother Robin (James Mitchum) join the family business. Under pressure from both out-of-town gangster Kogan (Jacques Aubuchon), who wants a piece of the local action, and Treasury agent Barrett (Gene Barry), who wants to destroy the moonshine business, Luke fights for his fast-fading way of life.
This labor advocacy film is about diseases plaguing miners in Kansas, Missouri and Oklahoma. Sponsored by the Tri-State Survey Committee, "Men and Dust" is a stylistically innovative documentary and a valuable ecological record of landscapes radically transformed by extractive industry.