유엔 평화봉사단인 더글라스(데이빗 튤리스 분)는 공무 수행차 남태평양 자바해 상공을 비행하다가 추락한다. 더글라스는 항해 중이던 몽고메리(발 킬머 분)란 과학자에게 구조되고 조난 사실을 알리기 위해 그들을 따라 낯선 열대섬에 상륙한다. 섬에는 노벨상을 수상한 유전학자 모로 박사(마론 브란도 분)가 살고 있었다. 더글라스는 그의 딸 아이사(페루자 벌크 분)를 만나 이국적이고 아름다운 용모에 매혹된다. 그런데, 그날 밤 몽고메리는 더글라스를 방에 가둬버린다. 수상한 낌새를 눈치챈 더글라스는 섬을 조사하기로 결심한다.
General Romero, leader of a small Latin American country, is showing the UN how he's taking care of his country's drug problems by publicly burning crops of marijuana. As soon as the inspectors leave, however, Romero quickly returns to business, producing and shipping the illegal crop. When his right-hand man is convinced by a crusading reporter to turn away from his life of crime and help bring his boss to justice, Romero vows to stop at nothing to prevent this traitor from talking.
A maniac butchers a fashion model on a Caribbean island and leaves the body to be eaten by rats. The model's sister suspects something isn't quite right with the police investagation and decides to go snooping on her own. With her friend, Fred, their investagations lead them to an unknown part of the island where they discover a monstrosity of a rat like man. The creature is killed by Fred, but the true horror of it's nature is just beginning...