Marmaduke é um dog alemão adolescente de 90 quilos muito bagunceiro, que mora com a família Winslow. Quando os Winslows mudam-se para Califórnia, Marmaduke apaixona-se pela linda afegã Jezebel e terá de passar por vários desafios para aprender que o caráter e a beleza interior são as verdadeiras provas de um ‘TOP DOG”.
A multiple murder investigation in a small hunting town focuses on one suspect, Wendy Sinclair, who operates a battered women's shelter where each of the victims' wives have sought shelter.
Four unemployed, uninspired, life loving 20-something guys decide to turn their backs on society and hit the road in the world's slowest little bus, taking things one mile at a time.
