Although she's only sixteen and looks even younger, Misao Makimachi is already a skilled and competent member of the Oniwabanshu ninja clan. That's fortunate for Misao, because her onimitsu talents may be all that keeps her alive when a journey in search of the leader of the clan, Aoshi Shinomori, leads her instead into a face-to-face encounter with an even more dangerous man and a plot to overthrow the Meiji government! Quickly enmeshed in the affairs of the legendary assassin Hitokiri Battosai, now known as Kenshin Himura, wielder of the reverse-blade sword, Misao finds herself pulled into the middle of a deadly intrigue against Makoto Shishio, who is orchestrating the conquest of all Japan - beginning with Kyoto!
Kenshin and Kaoru are married. Kenshin leaves Kaoru with their son, Kenji, to lead a revolution in China. But both of them suffer from a seemingly incurable disease. 15 years later, Kenshin tries to return home to his wife before she dies of grief. Flashbacks of Kenshin's previous encounters with friends and foes occur while Kenshin struggles to make it back home.
The war against the Tokugawa Shogunate ended years ago. But there are some who are not happy with the outcome. Shigure Takimi watched his friends and family get slashed down in the name of freedom and prosperity. Now he and a band of desparate rebels have sworn to settle one final score. Only one man stands in their way: Rurouni Kenshin. Will the former assassin take up his sword to fight again? When Shigure discovers Kenshin's true identity and his fight becomes a personal vendetta, the young hero will have no choice.
Black Jack is a master surgeon who possesses impeccable skills, enabling him to perform operations that are impossible for even the finest surgeons. He now is faced with his most difficult task to date and must challenge the limits of medical science...before it's too late!